Pseudoephedrine PSE is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes. Pseudoephedrine is a stimulantbut it is well known for shrinking swollen nasal mucous membranes, so it is often used as a decongestant. It reduces tissue hyperemiaedemaand nasal congestion commonly associated with colds or allergies. Other beneficial effects may include increasing the drainage of sinus secretions, and opening of obstructed Eustachian tubes. The same vasoconstriction action can also result in hypertensionwhich is a noted side effect of pseudoephedrine.
Pseudoephedrine can be used either as oral or as topical decongestant. However, due to its stimulating qualities, the oral preparation is more likely to cause adverse effects, including urinary retention. Pseudoephedrine is indicated for the treatment of nasal congestion, sinus congestion and Eustachian tube congestion.
Pseudoephedrine is also used as a first-line prophylactic for recurrent priapism. Erection is largely a parasympathetic response, so the sympathetic action of pseudoephedrine may serve to relieve this condition.
Treatment for urinary incontinence is an off-label use "unlabeled use" for these medications. Common adverse drug reactions ADRs associated with pseudoephedrine therapy include central nervous system stimulation, insomnia, nervousness, excitability, dizziness and anxiety.
Infrequent ADRs include tachycardia or palpitations. Rarely, pseudoephedrine therapy may be associated with mydriasis dilated pupilshallucinationsarrhythmiashypertensionseizures and ischemic colitis ;  as well as severe skin reactions known as recurrent pseudo-scarlatina, systemic contact dermatitis, and nonpigmenting fixed drug eruption.
Pseudoephedrine is contraindicated in patients with diabetes mellituscardiovascular diseasesevere or uncontrolled hypertensionsevere coronary artery diseaseprostatic hypertrophyhyperthyroidismclosed angle glaucomaor by pregnant women.
Concomitant or recent previous fourteen days monoamine oxidase inhibitor use can lead to hypertensive reactions, including hypertensive crises. The antihypertensive effects of methyldopamecamylaminereserpine and veratrum alkaloids may be reduced by sympathomimetics.
Beta-adrenergic antagonists may also interact with sympathomimetics.Rich people jobs
Increase of ectopic pacemaker activity can occur when pseudoephedrine is used concomitantly with digitalis. Antacids increase the rate of pseudoephedrine absorption, while kaolin decreases it. Pseudoephedrine is a sympathomimetic amine.
Its principal mechanism of action relies on its direct action on the adrenergic receptor system. When these receptors are activated, the muscles contract, causing the blood vessels to constrict vasoconstriction. The constricted blood vessels now allow less fluid to leave the blood vessels and enter the nose, throat and sinus linings, which results in decreased inflammation of nasal membranes, as well as decreased mucus production.
Thus, by constriction of blood vessels, mainly those located in the nasal passages, pseudoephedrine causes a decrease in the symptoms of nasal congestion. There have been reports of off-label uses of pseudoephedrine for its stimulant properties. A study has also found that pseudophedrine can reduce milk production in breastfeeding women.
Its membership in the amphetamine class has made pseudoephedrine a sought-after chemical precursor in the illicit manufacture of methamphetamine and methcathinone.Important: The information below refers to products available in the United States that contain pseudoephedrine.
Brand names: SudoGestUnifed, nasofedNexafed Nasal Decongestant Drug class es : decongestants Pseudoephedrine systemic is used in the treatment of:. Drug class es : upper respiratory combinations. Brand names: Ursinus Drug class es : upper respiratory combinations. Brand names: Lemohist Plus Drug class es : upper respiratory combinations. Brand names: Polaramine Expectorant Drug class es : upper respiratory combinations.
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Skip to Content. International Drugs Ingredients pseudoephedrine Print Share. Pseudoephedrine Important: The information below refers to products available in the United States that contain pseudoephedrine.
Email address. Select one or more newsletters to continue. Explore Apps. About About Drugs. All rights reserved.Drug information provided by: IBM Micromedex. Pseudoephedrine is used to relieve nasal or sinus congestion caused by the common cold, sinusitis, and hay fever and other respiratory allergies.
It is also used to relieve ear congestion caused by ear inflammation or infection.
Pseudoephedrine Abuse: Symptoms, Effects, & More
Do not give any over-the-counter OTC cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
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Visit now. Explore now. Choose a degree. Get updates. Give today. Drugs and Supplements Pseudoephedrine Oral Route. Products and services. Free E-newsletter Subscribe to Housecall Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Drug information provided by: IBM Micromedex. To help prevent trouble in sleeping, take the last dose of pseudoephedrine for each day a few hours before bedtime. If you have any questions about this, check with your doctor.
Take this medicine only as directed. Do not take more of it, do not take it more often, and do not take it for a longer period of time than recommended on the label usually 7 daysunless otherwise directed by your doctor.Vue echarts document is not defined
To do so may increase the chance of side effects. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.
Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.Back to Medicines A to Z. Nasal congestion is caused when blood vessels in the cavities in your nose sinuses become swollen.
You can buy pseudoephedrine from pharmacies and supermarkets. It comes as tablets and a liquid that you swallow. Pseudoephedrine also comes mixed with other medicines to treat the symptoms of coughs, colds and allergies. You can sometimes give pseudoephedrine to children over 6 years with a stuffy nose, depending on their age and symptoms.
Ask a pharmacist for advice. Do not give pseudoephedrine to children under 6 years. This includes cough and cold medicines containing pseudoephedrine. Always check the label. Pseudoephedrine is not suitable for some people. Tell a pharmacist or doctor if you have:. The instructions will be different depending on the type of treatment you buy and the other medicines it's mixed with. If you have bought pseudoephedrine or any medicine containing pseudoephedrine from a pharmacy or supermarket, follow the instructions that come with the packet or ask a pharmacist for advice.
Adults and children aged 12 to 17 years: take one 60mg tablet or two 5ml spoon 10ml of liquid up to 4 times a day. Children aged 6 to 11 years: take half a tablet 30mg or one 5ml spoon of liquid up to 4 times a day. You can take pseudoephedrine tablets and liquid with or without food.
Always take the tablets with a glass of water. Liquid medicines containing pseudoephedrine come with a plastic syringe or spoon to help you measure out the right dose. If you do not have a syringe or spoon, ask a pharmacist for one. Do not use a kitchen teaspoon as you will not get the right amount. It can make you restless or your heartbeat fast, and make you feel sick or vomit. You may also have difficulty peeing.
Get someone else to drive you or call for an ambulance. In rare cases, it's possible to have a serious allergic reaction anaphylaxis to pseudoephedrine.
Pseudoephedrine is not recommended in pregnancy because it can reduce the blood flow in the placenta and to the baby. Pseudoephedrine can reduce the amount of milk you make, especially if you have not been breastfeeding for long. If you're taking pseudoephedrine mixed with other medicines, you must check with a pharmacist or doctor whether it's safe to breastfeed.
Some medicines and pseudoephedrine interfere with each other and increase the chances of you having side effects.
Before taking any other medicines, check the label to see if they contain aspirin, paracetamol or ibuprofen. There's very little information about taking herbal remedies and supplements with pseudoephedrine. Tell a doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. This helps mucus and air flow more freely in the cavities in your nose sinuseshelping you to breathe more easily. Pseudoephedrine starts to work in 15 to 30 minutes, but you should feel a lot better after 30 to 60 minutes.
Pseudoephedrine can be taken for a few days, usually up to 5 to 7 days, for the short-term relief of a stuffy or blocked nose. Pseudoephedrine works by narrowing the blood vessels in your nose, but it also narrows the blood vessels in other parts of your body. If you have any heart problems or you're worried about this, speak to a pharmacist or doctor about a different treatment.
It's a good idea to limit food and drink containing caffeine such as coffee, tea, cola and chocolate. Caffeine can increase your risk of side effects, like feeling more restless or shaky and increasing your heartbeat.Lig (18)UkrainePremier League (6)Persha Liga (9)United StatesMLSNASLUruguayUzbekistanVenezuela (1)VietnamWalesPremier (4)Division 1 (4)UAEEuro 2016Confederations cupWorld cupQual.
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Everything was quiet perfect, the receptions on the hotels, the bedrooms, and the places you recommended to see. As I said before the standard of accommodation was excellent as the rental car. The standards of the meals were good. The itinerary was excellent (we loved Heimaey, especially the hotel). Well, we were a bit surprised (positively) because we didn't have any references at all about your services (we knew about your travel agency by google), and we can say that if we return to a nordic country maybe it will be using the services of Nordic Visitor.
The only thing we are disappointed is to never knew the person that make this perfect travel organization. But still thank you for all. I was initially skeptical of what kind of service we were going to be getting, but everything, top to bottom, was very professional and well put together. We didn't have much communication with Dagny, but after having met her in person, we felt like we could ask anything of her. We were really regretful that we didn't get to visit the Nordic Visitor office on our last day to give a video review, and to thank her in person.
Have already recommended NV once from our Iceland trip and will absolutely recommend again. Christoph was also wonderful- did a fantastic job in customizing the trip for us (combination of 2 trips), and was also quick to respond and communicate via email.
We will definitely book again- the only negative is that the time went by too quickly.
We have just arrived back from a most memorable and enjoyable trip which you organised for us. Right from the beginning of our email correspondence, we have been impressed by the quality, dedication and effort you have put into making our tour of Scotland enjoyable. Thank you for going beyond what I would normally expect.
The tour and the associated paperwork and maps which you arranged were all marvellous and a good representation of Scotland. Whilst I thought that two days on Skye would be far too long, it was just right.
Thank you again for your assistance and I shall endeavour through trip advisor and friends to spread the word about your wonderful company. Nordic appear to be professional, aware of the best locations to visit and stay. The suggested tour is well balanced between places to see and covering the distance.
We were very impressed with the standard of accommodation given that we only booked "standard". We're just on the train back from Edinburgh, and wanted to say a big thank you for all your help organising our trip. We had an amazing time travelling round Scotland, and all the organization couldn't have been better.
Everything went so smoothly - all the information you provided was so detailed and really helped us make the most of our trip. And all the accommodation was just amazing!.Purification and Drying: Acetone
We've had such a great time, thank you again for all your help. I will definitely recommend Nordic Visitor to my friends.
We were glad to have the printed maps supplied by Nordic Visitor. We were very pleased with the decision to up-grade from 'Standard' to 'Superior' accomodation.
The 'Commodore Class' on the Ferry was very welcome. The car was upgraded as well, fantastic. We loved staying at the Basecamp Trapper's hotel. The place was really interesting and the staff very nice. We pass along a special thanks to Lise at the hotel for her exceptional customer service and friendly personality.
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